Actual facts about bacterial meningitis
نویسندگان
چکیده
Background Bacterial meningitis still represents an important chapter in the present infectious pathology, despite the increasing progress in the prophylaxis and prevention measures. Apart from tuberculous etiology, and of course the well-known classical etiologies – meningococcal, pneumococcal, Haemophilus influenzae, staphylococcal and Gram-negative bacteria – new entities that need to be evaluated seem to appear. Objectives: 1. To determine the incidence of bacterial meningitis in the last years, in comparison with the international situation encountered in this pathology. 2. To detect new predisposing and risk factors for meningitis. 3. The important role of procalcitonin and other markers for the quick diagnosis of meningitis. 4. The utilization in the current medical practice of modern molecular diagnostic tests, especially for the severe and atypical cases.
منابع مشابه
Clinical, Paraclinical, and Antimicrobial Resistance Features of Community-Acquired Acute Bacterial Meningitis at a Large Infectious Diseases Ward in Tehran, Iran
In this study demographic, clinical, paraclinical, microbiological, and therapeutic features of patients with community-acquired acute bacterial meningitis admitted to a referral center for infectious diseases in Iran, have been evaluated. Medical records of adult (> 18 years) individuals with confirmed diagnosis of community-acquired bacterial meningitis during a 4-year period were retrospecti...
متن کاملRelative expression of fibroblast growth factor-1 in the cerebrospinal fluid of patients with bacterial meningitis; A Western Blot analysis
Meningitis is an inflammation of the membranes that surround the brain and spinal cord, thereby involving the arachnoid, the pia and the cerebrospinal fluid (CSF). It is divided into viral and bacterial meningitis. For different reasons the diagnosis of bacterial meningitis is very important. The examination of CSF samples may provide information about causative microorganism. The sensivity of ...
متن کاملClinical, Paraclinical, and Antimicrobial Resistance Features of Community-Acquired Acute Bacterial Meningitis at a Large Infectious Diseases Ward in Tehran, Iran
In this study demographic, clinical, paraclinical, microbiological, and therapeutic features of patients with community-acquired acute bacterial meningitis admitted to a referral center for infectious diseases in Iran, have been evaluated. Medical records of adult (> 18 years) individuals with confirmed diagnosis of community-acquired bacterial meningitis during a 4-year period were retrospecti...
متن کاملارزش تشخیصی سطح سرمی پروکلسیتونین در افتراق مننژیت باکتریال از غیرباکتریال در کودکان یک ماهه تا 18 ساله مرکز طبی کودکان ، 83-1382
Background: Bacterial meningitis is a fatal disease with high mortality and morbidity that needs emergency management. But due to nonspecific signs and symptoms it;aposs diagnosis in children is difficult. Recently procalcitonin has been used for diagnosis of serious bacterial infections like bacterial meningitis. We conducted a prospective study in children for evaluation of procalcitonin in d...
متن کاملConcentration of soluble form of hepatocyte growth factor receptor in cerebrospinal fluid and serum of patients with bacterial and viral meningitis
Abstract Background and objectives: C-Met is a proto-oncogene that encodes a protein known as hepatocyte growth factor receptor (HGFR). The HGF receptor possesses tyrosine -kinase activity and it is essential for embryonic development, wound healing and cancer. Many proteins are proteolytically released from the surface by a process known as ectodomain shedding. Shedding occurs under normal phy...
متن کامل